| # | Ticker | MCap | Price | Chg% | Volume | Avg Vol | Vol× | 52w% | ATR% | IPO Date |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | FOLD | $4.5B | $14.49 | +0.00% | — | 3.2M | 0.0× | 100% | 0.08% | 2007-05-31 |
| 2 | SHC | $4.5B | $15.85 | +1.98% | 582.5K | 3.8M | 0.2× | 56% | 2.85% | 2020-11-20 |
| 3 | BLLN | $4.5B | $97.17 | +6.76% | 203.2K | 658.0K | 0.3× | 46% | 9.38% | 2025-11-06 |
| 4 | TVTX | $4.4B | $47.25 | -1.08% | 778.1K | 2.4M | 0.3× | 96% | 4.70% | 2012-11-08 |
| 5 | SYRE | $4.4B | $72.48 | -0.04% | 113.4K | 1.2M | 0.1× | 90% | 5.58% | 2016-04-07 |
| 6 | TWST | $4.3B | $68.96 | +7.46% | 541.2K | 1.5M | 0.4× | 100% | 7.03% | 2018-10-31 |
| 7 | RDNT | $4.3B | $54.58 | +1.38% | 99.4K | 859.2K | 0.1× | 11% | 5.64% | 1997-01-03 |
| 8 | MANE | $4.3B | $101.82 | +1.69% | 133.2K | 647.8K | 0.2× | 81% | 6.49% | 2026-02-04 |
| 9 | XENE | $4.2B | $53.72 | -0.33% | 470.8K | 966.6K | 0.5× | 71% | 2.80% | 2014-11-05 |
| 10 | HNGE | $4.2B | $54.05 | +0.88% | 263.7K | 1.4M | 0.2× | 75% | 4.14% | 2025-05-22 |
| 11 | NAMS | $4.2B | $35.51 | -2.89% | 239.9K | 1.4M | 0.2× | 73% | 6.58% | 2021-02-09 |
| 12 | AMRX | $4.1B | $12.93 | +1.21% | 315.1K | 1.6M | 0.2× | 70% | 2.91% | 2018-05-07 |
| 13 | LIVN | $4.0B | $72.02 | -2.54% | 154.9K | 843.4K | 0.2× | 89% | 3.51% | 2015-10-19 |
| 14 | DOCS | $3.9B | $21.02 | +3.78% | 995.9K | 4.8M | 0.2× | 7% | 5.64% | 2021-06-24 |
| 15 | ERAS | $3.9B | $12.51 | +0.32% | 1.5M | 8.0M | 0.2× | 49% | 6.49% | 2021-07-16 |
| 16 | CRNX | $3.9B | $36.68 | -0.30% | 112.6K | 1.2M | 0.1× | 34% | 5.74% | 2018-07-18 |
| 17 | KNSA | $3.9B | $51.42 | -0.81% | 109.8K | 773.0K | 0.1× | 75% | 3.62% | 2018-05-25 |
| 18 | CPRX | $3.8B | $31.32 | -0.01% | 548.5K | 3.0M | 0.2× | 91% | 0.25% | 2006-11-08 |
| 19 | NVST | $3.8B | $23.51 | +0.86% | 867.7K | 3.5M | 0.2× | 45% | 4.38% | 2019-09-18 |
| 20 | MMSI | $3.8B | $63.20 | +1.08% | 133.2K | 809.7K | 0.2× | 9% | 3.11% | 1990-05-14 |
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