GPCR

Structure Therapeutics Inc. NASDAQ Listed Feb 3, 2023

Healthcare ·Biotechnology ·US · structuretx.com

$39.05

After hrs $38.94 -0.54%

Mkt Cap $2.2B

52w Low $15.80 29.4% of range 52w High $94.90

50d MA $51.72 200d MA $45.02

P/E (TTM) -17.6x

EV/EBITDA -24.3x

P/B 1.6x

Debt/Equity 0.0x

ROE -9.3%

P/FCF -18.2x

RSI (14) —

ATR (14) —

Beta -1.25

50d MA $51.72

200d MA $45.02

Avg Volume 959.3K

About

Structure Therapeutics Inc., a clinical stage global biopharmaceutical company, develops and delivers novel oral therapeutics to treat a range of chronic diseases with unmet medical needs. Its lead product candidate is GSBR-1290, an oral and biased small molecule agonist of glucagon-like-peptide-1 receptor, a validated G-protein-coupled receptors (GPCRs) drug target for type-2 diabetes mellitus an…

Recent Earnings

Date	Time	Est	Rptd	Surp	Base	Gap%	D1%	D2%	D3%	D4%	D5%	Guide ▲★
Feb 26, 2026	AMC	-0.35	-0.49	-40.0%	64.75	-1.0%	-2.7%	-2.9%	-2.6%	-2.5%	-7.8%	—
Nov 6, 2025	AMC	-0.36	-0.37	-2.8%	33.47	+0.7%	-1.9%	+1.3%	+4.2%	+7.3%	+4.6%	—
Aug 6, 2025	AMC	-0.28	-0.36	-28.6%	16.31	+8.5%	-0.7%	+0.0%	+7.4%	+14.9%	+17.5%	—
May 8, 2025	AMC	-0.24	-0.27	-12.5%	26.82	-0.6%	-4.7%	-8.2%	-10.9%	-11.2%	-8.9%	—
Feb 27, 2025	AMC	-0.23	-0.22	+4.3%	22.82	+1.7%	+4.1%	-2.1%	-1.4%	-1.1%	+3.1%	—
Nov 13, 2024	AMC	-0.19	-0.20	-5.3%	36.37	-1.0%	+3.6%	-6.0%	-12.7%	-9.9%	-10.1%	—
Aug 8, 2024	AMC	-0.23	-0.18	+21.7%	34.49	+4.3%	-2.1%	-3.8%	-0.5%	+5.1%	+5.9%	—
May 9, 2024	AMC	-0.21	-0.19	+9.5%	38.65	-4.5%	-7.3%	-6.9%	-7.6%	-6.7%	-7.2%	—
Mar 8, 2024	AMC	-0.21	-0.17	+19.0%	36.86	+1.9%	-4.7%	-4.3%	-8.0%	-4.6%	-4.4%	—
Nov 14, 2023	AMC	-0.29	-0.62	-113.8%	53.59	+0.9%	-9.8%	-10.5%	+0.3%	-0.2%	-4.2%	—
Aug 10, 2023	AMC	-0.28	-0.60	-114.3%	29.35	-3.5%	-6.1%	-7.6%	-7.0%	-7.7%	-6.2%	—
May 11, 2023	AMC	-0.41	-0.25	+39.0%	25.00	+1.5%	+5.6%	+4.0%	-1.2%	-7.1%	-9.9%	—

Recent Analyst Ratings

Date	Firm	Action	Grade	Target	Base	Open	Gap%	D1%	D2%	D3%	D4%	D5%
Apr 27	Canaccord Genuity	Initiates	Buy	$101	$45.49	$45.79	+0.7%	-0.4%	-4.2%	-9.1%	-8.9%	-7.2%
Mar 16	HC Wainwright & Co.	Maintains	Buy → Buy	—	$53.75	$56.58	+5.3%	+5.4%	+4.5%	-3.5%	-6.1%	-9.6%
Mar 2	HC Wainwright & Co.	Maintains	Buy → Buy	—	$62.98	$61.88	-1.7%	-0.1%	+0.1%	+0.2%	-5.2%	-8.3%
Feb 27	Citizens	Maintains	Market Outperform → Market Outperform	—	$64.75	$64.13	-1.0%	-2.7%	-2.9%	-2.6%	-2.5%	-7.8%
Jan 22	JP Morgan	Maintains	Overweight → Overweight	—	$93.79	$93.79	+0.0%	-2.0%	-3.6%	-4.5%	-4.6%	-5.1%
Jan 20	Guggenheim	Maintains	Buy → Buy	—	$88.64	$88.36	-0.3%	+2.7%	+5.8%	+3.6%	+2.0%	+1.0%
Dec 19	HC Wainwright & Co.	Maintains	Buy → Buy	—	$62.45	$66.03	+5.7%	+4.0%	+1.3%	+14.2%	+11.6%	+9.4%
Dec 12	Morgan Stanley	Maintains	Overweight → Overweight	—	$67.44	$68.61	+1.7%	-0.6%	-3.9%	-8.5%	-11.1%	-7.4%
Dec 12	Citizens	Maintains	Market Outperform → Market Outperform	—	$67.44	$68.61	+1.7%	-0.6%	-3.9%	-8.5%	-11.1%	-7.4%
Dec 11	Jefferies	Maintains	Buy → Buy	—	$68.94	$69.30	+0.5%	-2.2%	-2.7%	-6.0%	-10.5%	-13.0%
Dec 9	Stifel	Maintains	Buy → Buy	—	$69.98	$67.86	-3.0%	-4.6%	-1.5%	-3.6%	-4.2%	-7.4%
Dec 9	Clear Street	Maintains	Buy → Buy	—	$69.98	$67.86	-3.0%	-4.6%	-1.5%	-3.6%	-4.2%	-7.4%
Dec 9	Citigroup	Maintains	Buy → Buy	—	$69.98	$67.86	-3.0%	-4.6%	-1.5%	-3.6%	-4.2%	-7.4%
Aug 7	Guggenheim	Maintains	Buy → Buy	—	$16.31	$17.69	+8.5%	-0.7%	+0.0%	+7.4%	+14.9%	+17.5%
Aug 7	HC Wainwright & Co.	Maintains	Buy → Buy	—	$16.31	$17.69	+8.5%	-0.7%	+0.0%	+7.4%	+14.9%	+17.5%
Aug 7	JMP Securities	Maintains	Market Outperform → Market Outperform	—	$16.31	$17.69	+8.5%	-0.7%	+0.0%	+7.4%	+14.9%	+17.5%
Jun 23	Cantor Fitzgerald	Maintains	Overweight → Overweight	—	$21.73	$21.91	+0.8%	+1.7%	+3.0%	+0.3%	-3.0%	-3.0%
Jun 23	JMP Securities	Maintains	Market Outperform → Market Outperform	—	$21.73	$21.91	+0.8%	+1.7%	+3.0%	+0.3%	-3.0%	-3.0%
May 12	HC Wainwright & Co.	Maintains	Buy → Buy	—	$25.57	$26.38	+3.2%	-3.7%	-6.6%	-6.8%	-4.5%	-1.6%
Apr 22	HC Wainwright & Co.	Maintains	Buy → Buy	—	$23.10	$23.17	+0.3%	-0.3%	+1.0%	+2.4%	+2.8%	+2.3%
Feb 28	Citizens Capital Markets	Maintains	Market Outperform → Market Outperform	—	$22.82	$23.20	+1.7%	+4.1%	-2.1%	-1.4%	-1.1%	+3.1%
Dec 20	HC Wainwright & Co.	Maintains	Buy → Buy	—	$29.97	$30.79	+2.7%	-6.9%	-4.6%	-5.7%	-1.4%	-3.1%
Dec 19	HC Wainwright & Co.	Maintains	Buy → Buy	—	$27.90	$27.42	-1.7%	+7.4%	+0.0%	+2.4%	+1.3%	+5.9%
Dec 18	JMP Securities	Maintains	Market Outperform → Market Outperform	—	$31.48	$29.60	-6.0%	-11.4%	-4.8%	-11.4%	-9.2%	-10.3%
Sep 23	Cantor Fitzgerald	Maintains	Overweight → Overweight	—	$41.92	$45.00	+7.3%	+1.0%	+5.0%	+0.1%	-0.9%	-0.4%
Sep 16	Cantor Fitzgerald	Maintains	Overweight → Overweight	—	$40.84	$40.63	-0.5%	-2.1%	-5.9%	-6.3%	-5.1%	+2.6%
Sep 9	Cantor Fitzgerald	Maintains	Overweight → Overweight	—	$36.95	$37.13	+0.5%	-4.7%	-6.8%	+7.3%	+9.0%	+10.5%
Aug 19	Cantor Fitzgerald	Maintains	Overweight → Overweight	—	$37.12	$37.23	+0.3%	+8.0%	+8.5%	+6.8%	+5.5%	+7.2%
Aug 15	Cantor Fitzgerald	Maintains	Overweight → Overweight	—	$36.24	$36.83	+1.6%	+0.7%	+2.4%	+10.7%	+11.1%	+9.4%
Aug 9	JMP Securities	Maintains	Market Outperform → Market Outperform	—	$34.49	$35.97	+4.3%	-2.1%	-3.8%	-0.5%	+5.1%	+5.9%
Jul 1	Cantor Fitzgerald	Maintains	Overweight → Overweight	—	$39.27	$40.01	+1.9%	+1.9%	-1.4%	-4.6%	-3.8%	-5.2%
Jun 20	Cantor Fitzgerald	Maintains	Overweight → Overweight	—	$47.52	$46.91	-1.3%	-1.6%	-4.1%	-8.1%	-15.9%	-20.3%
Jun 17	Cantor Fitzgerald	Maintains	Overweight → Overweight	—	$48.17	$48.39	+0.5%	+0.9%	-1.3%	-2.9%	-5.4%	-9.3%
Jun 7	BMO Capital	Maintains	Outperform → Outperform	—	$55.63	$55.66	+0.1%	-4.6%	-4.9%	-10.0%	-6.5%	-7.2%
Jun 3	Cantor Fitzgerald	Maintains	Overweight → Overweight	—	$34.20	$35.45	+3.7%	+54.2%	+58.7%	+64.6%	+62.7%	+55.2%
May 10	JMP Securities	Maintains	Market Outperform → Market Outperform	—	$38.65	$36.92	-4.5%	-7.3%	-6.9%	-7.6%	-6.7%	-7.2%
May 3	Cantor Fitzgerald	Maintains	Overweight → Overweight	—	$38.99	$39.55	+1.4%	+0.8%	+1.9%	+0.9%	+0.6%	-0.9%
Apr 18	Cantor Fitzgerald	Maintains	Overweight → Overweight	—	$37.07	$36.93	-0.4%	-2.4%	-1.9%	-2.8%	-2.6%	-1.7%
Mar 8	JMP Securities	Maintains	Market Outperform → Market Outperform	—	$36.01	$36.79	+2.2%	+2.4%	-2.5%	-2.0%	-5.9%	-2.3%
Nov 20	JMP Securities	Maintains	Market Outperform → Market Outperform	—	$53.77	$54.67	+1.7%	-0.6%	-4.5%	-4.5%	-4.2%	-2.5%
Nov 15	JMP Securities	Maintains	Market Outperform → Market Outperform	—	$53.59	$54.09	+0.9%	-9.8%	-10.5%	+0.3%	-0.2%	-4.2%
Oct 27	Piper Sandler	Maintains	Overweight → Overweight	—	$70.00	$69.00	-1.4%	-2.6%	-0.4%	+6.1%	+5.5%	+2.7%
Oct 26	Piper Sandler	Maintains	Overweight → Overweight	—	$67.61	$68.85	+1.8%	+3.5%	+0.8%	+3.1%	+9.9%	+9.3%
Oct 3	BMO Capital	Maintains	Outperform → Outperform	—	$56.60	$58.04	+2.5%	+4.1%	-3.6%	-2.8%	-2.6%	+2.5%
Sep 29	Jefferies	Maintains	Buy → Buy	—	$37.47	$65.09	+73.7%	+34.6%	+51.1%	+57.3%	+45.6%	+46.9%
Feb 28	Jefferies	Maintains	Buy → Buy	—	$24.00	$24.20	+0.8%	+6.5%	-4.5%	-4.9%	+10.6%	+8.3%
Feb 28	BMO Capital	Maintains	Outperform → Outperform	—	$24.00	$24.20	+0.8%	+6.5%	-4.5%	-4.9%	+10.6%	+8.3%
Feb 28	Guggenheim	Maintains	Buy → Buy	—	$24.00	$24.20	+0.8%	+6.5%	-4.5%	-4.9%	+10.6%	+8.3%

Recent Filings

8-K

Structure Therapeutics Inc. -- 8-K Filing

Structure Therapeutics reported Q4 2025 results and positioned its oral obesity treatment candidates to capture market share as the obesity market expands toward new oral therapeutic options.

Feb 26

Data updated apr 26, 2026 10:44am · Source: massive.com