SLN

Silence Therapeutics plc NASDAQ Listed Sep 8, 2020

Healthcare ·Biotechnology ·GB · silence-therapeutics.com

$7.36

After hrs $7.36 -0.20%

Mkt Cap $347.6M

52w Low $3.54 78.6% of range 52w High $8.40

50d MA $6.40 200d MA $5.93

P/E (TTM) -3.8x

EV/EBITDA -3.1x

P/B 5.4x

Debt/Equity 0.0x

ROE -142.2%

P/FCF -4.6x

RSI (14) —

ATR (14) —

Beta 1.33

50d MA $6.40

200d MA $5.93

Avg Volume 322.0K

About

Silence Therapeutics plc, a biotechnology company, focuses on the discovery and development of novel ribonucleic acid (RNA) therapeutics in hematology, cardiovascular, and other rare and metabolic indications. The company's platform includes mRNAi GalNAc Oligonucleotide Discovery platform designed to accurately target specific disease-associated genes in the liver. It designs short interfering RNA…

Recent Earnings

Date	Time	Est	Rptd	Surp	Base	Gap%	D1%	D2%	D3%	D4%	D5%	Guide ▲★
Mar 5, 2026	AMC	-0.32	-0.25	+21.9%	5.50	-1.1%	+13.3%	+12.5%	+14.0%	+26.9%	+26.7%	—
Nov 6, 2025	AMC	-0.40	-0.45	-12.5%	6.45	-1.1%	+2.0%	-1.6%	+4.2%	+4.3%	+7.3%	—
Aug 7, 2025	AMC	-0.27	-0.54	-100.0%	5.38	-2.4%	-6.3%	-5.4%	+3.9%	+8.7%	+4.6%	—
May 8, 2025	AMC	-0.18	-0.60	-233.3%	3.56	+0.6%	+3.9%	+7.6%	+15.4%	+14.0%	+12.6%	—
Feb 27, 2025	AMC	-0.45	0.27	+160.0%	4.72	-0.4%	-4.7%	-8.5%	-5.1%	+0.2%	+0.4%	—
Nov 14, 2024	AMC	-0.42	-0.75	-78.6%	13.98	+0.1%	-9.2%	-21.2%	-50.1%	-50.4%	-45.1%	—
May 16, 2024	AMC	-0.23	-0.05	+78.3%	22.94	+1.0%	+0.3%	+1.8%	+4.2%	+1.2%	-4.1%	—
Nov 14, 2023	AMC	-0.56	-0.28	+50.0%	9.22	+2.6%	+2.2%	+0.9%	-1.3%	+7.5%	+16.7%	—
Aug 16, 2023	AMC	-0.59	-0.36	+39.0%	6.50	+0.0%	+4.8%	+7.5%	+7.5%	+14.9%	+30.6%	—
May 16, 2023	AMC	-0.51	-0.35	+31.4%	5.96	-0.2%	-8.6%	+1.2%	+0.3%	+0.7%	+1.3%	—
Nov 10, 2022	AMC	-0.60	-0.25	+58.3%	12.20	-1.3%	+6.6%	+13.9%	+13.0%	+8.3%	+0.8%	—
Aug 11, 2022	AMC	-0.60	-1.20	-99.5%	9.95	+0.5%	-1.4%	-1.9%	-2.7%	-13.6%	-3.4%	—

Recent Analyst Ratings

Date	Firm	Action	Grade	Target	Base	Open	Gap%	D1%	D2%	D3%	D4%	D5%
Mar 13	HC Wainwright & Co.	Maintains	Buy → Buy	—	$6.97	$7.00	+0.4%	-1.0%	+5.5%	-0.9%	-4.9%	-8.5%
Sep 16	HC Wainwright & Co.	Maintains	Buy → Buy	—	$4.73	$4.74	+0.2%	+2.5%	+5.9%	+6.3%	+3.4%	+6.6%
Aug 8	Chardan Capital	Maintains	Buy → Buy	—	$5.38	$5.25	-2.4%	-6.3%	-5.4%	+3.9%	+8.7%	+4.6%
Jun 13	HC Wainwright & Co.	Maintains	Buy → Buy	—	$5.59	$5.50	-1.6%	-4.7%	-9.5%	-3.9%	+1.3%	+6.4%
Jun 13	Chardan Capital	Maintains	Buy → Buy	—	$5.59	$5.50	-1.6%	-4.7%	-9.5%	-3.9%	+1.3%	+6.4%
May 9	Morgan Stanley	Maintains	Overweight → Overweight	—	$3.56	$3.58	+0.6%	+3.9%	+7.6%	+15.4%	+14.0%	+12.6%
May 9	Goldman Sachs	Maintains	Sell → Sell	—	$3.56	$3.58	+0.6%	+3.9%	+7.6%	+15.4%	+14.0%	+12.6%
May 9	Chardan Capital	Maintains	Buy → Buy	—	$3.56	$3.58	+0.6%	+3.9%	+7.6%	+15.4%	+14.0%	+12.6%
Mar 7	HC Wainwright & Co.	Maintains	Buy → Buy	—	$4.74	$4.75	+0.2%	+2.3%	-5.1%	-11.0%	-10.3%	-14.3%
Mar 5	Morgan Stanley	Maintains	Overweight → Overweight	—	$4.48	$4.46	-0.4%	+5.6%	+5.8%	+8.3%	+0.4%	-5.8%
Mar 4	BMO Capital	Maintains	Outperform → Outperform	—	$4.32	$4.18	-3.2%	+3.7%	+9.5%	+9.7%	+12.3%	+4.2%
Mar 4	Goldman Sachs	Maintains	Sell → Sell	—	$4.32	$4.18	-3.2%	+3.7%	+9.5%	+9.7%	+12.3%	+4.2%
Feb 3	HC Wainwright & Co.	Maintains	Buy → Buy	—	$5.33	$5.13	-3.8%	-5.1%	+5.3%	+13.5%	+7.9%	-6.0%
Jan 29	HC Wainwright & Co.	Maintains	Buy → Buy	—	$5.34	$5.35	+0.2%	-1.9%	-1.7%	-0.2%	-5.2%	+5.1%
Dec 10	Chardan Capital	Maintains	Buy → Buy	—	$7.99	$8.02	+0.4%	-7.4%	-19.3%	-17.4%	-19.3%	-15.6%
Dec 9	HC Wainwright & Co.	Maintains	Buy → Buy	—	$8.52	$8.45	-0.8%	-6.2%	-13.1%	-24.3%	-22.5%	-24.3%
Nov 20	HC Wainwright & Co.	Maintains	Buy → Buy	—	$6.97	$7.10	+1.9%	-0.6%	+10.2%	+0.6%	+3.4%	+7.0%
Nov 15	HC Wainwright & Co.	Maintains	Buy → Buy	—	$13.98	$14.00	+0.1%	-9.2%	-21.2%	-50.1%	-50.4%	-45.1%
Nov 14	Chardan Capital	Maintains	Buy → Buy	—	$15.24	$15.20	-0.3%	-8.3%	-16.7%	-27.7%	-54.3%	-54.5%
Oct 8	Morgan Stanley	Maintains	Overweight → Overweight	—	$18.61	$18.60	-0.1%	+4.5%	+3.7%	+3.2%	+5.6%	+0.9%
Aug 30	HC Wainwright & Co.	Maintains	Buy → Buy	—	$18.75	$18.66	-0.5%	+1.8%	+2.2%	+2.7%	+0.5%	-0.5%
Aug 16	Chardan Capital	Maintains	Buy → Buy	—	$16.77	$16.37	-2.4%	-6.4%	-5.2%	-5.2%	-5.5%	-7.4%
Jun 28	Morgan Stanley	Maintains	Overweight → Overweight	—	$19.00	$20.00	+5.3%	+0.0%	-1.4%	-4.9%	-5.4%	-4.2%
Jun 28	Chardan Capital	Maintains	Buy → Buy	—	$19.00	$20.00	+5.3%	+0.0%	-1.4%	-4.9%	-5.4%	-4.2%
Jun 27	HC Wainwright & Co.	Maintains	Buy → Buy	—	$18.31	$18.36	+0.3%	+3.8%	+3.8%	+2.3%	-1.4%	-1.9%
Jun 20	HC Wainwright & Co.	Maintains	Buy → Buy	—	$18.90	$19.50	+3.2%	+0.0%	+4.0%	+7.7%	+5.6%	-3.1%
May 31	HC Wainwright & Co.	Maintains	Buy → Buy	—	$21.81	$21.81	+0.0%	-3.8%	-5.4%	-9.0%	-8.3%	-6.9%
May 24	HC Wainwright & Co.	Maintains	Buy → Buy	—	$22.00	$22.45	+2.0%	-0.4%	+0.4%	-2.1%	-0.9%	-4.6%
May 17	Chardan Capital	Maintains	Buy → Buy	—	$22.94	$23.17	+1.0%	+0.3%	+1.8%	+4.2%	+1.2%	-4.1%
May 17	HC Wainwright & Co.	Maintains	Buy → Buy	—	$22.94	$23.17	+1.0%	+0.3%	+1.8%	+4.2%	+1.2%	-4.1%
Apr 22	Morgan Stanley	Maintains	Overweight → Overweight	—	$22.64	$22.64	+0.0%	-0.6%	-0.6%	-1.6%	-4.5%	-4.5%
Mar 15	HC Wainwright & Co.	Maintains	Buy → Buy	—	$23.83	$23.97	+0.6%	-4.2%	+0.8%	-2.1%	-3.9%	-4.8%
Mar 14	Chardan Capital	Maintains	Buy → Buy	—	$25.61	$27.27	+6.5%	-7.0%	-10.8%	-6.2%	-8.9%	-10.5%
Mar 14	Morgan Stanley	Maintains	Overweight → Overweight	—	$25.61	$27.27	+6.5%	-7.0%	-10.8%	-6.2%	-8.9%	-10.5%
Mar 13	HC Wainwright & Co.	Maintains	Buy → Buy	—	$25.90	$24.60	-5.0%	-1.1%	-8.0%	-11.8%	-7.3%	-9.9%
Feb 22	HC Wainwright & Co.	Maintains	Buy → Buy	—	$23.80	$24.04	+1.0%	-3.1%	-1.4%	+0.9%	+7.3%	+7.9%
Jan 18	HC Wainwright & Co.	Maintains	Buy → Buy	—	$18.08	$18.41	+1.8%	+5.3%	+1.8%	+4.5%	+4.0%	+5.8%
Nov 17	HC Wainwright & Co.	Maintains	Buy → Buy	—	$9.30	$9.11	-2.0%	-2.2%	+6.6%	+15.7%	+24.2%	+26.4%
Aug 17	HC Wainwright & Co.	Maintains	Buy → Buy	—	$6.50	$6.50	+0.0%	+4.8%	+7.5%	+7.5%	+14.9%	+30.6%
Aug 17	Chardan Capital	Maintains	Buy → Buy	—	$6.50	$6.50	+0.0%	+4.8%	+7.5%	+7.5%	+14.9%	+30.6%
Jul 24	Morgan Stanley	Maintains	Overweight → Overweight	—	$5.56	$5.74	+3.2%	-4.9%	-8.8%	-3.6%	-3.2%	-1.1%
Jul 17	Morgan Stanley	Maintains	Overweight → Overweight	—	$5.80	$5.99	+3.3%	+1.2%	+0.0%	-11.4%	-7.9%	-4.1%
Jun 26	Morgan Stanley	Maintains	Overweight → Overweight	—	$6.65	$6.71	+0.9%	-2.3%	-2.3%	-4.4%	-12.6%	-17.3%
May 18	HC Wainwright & Co.	Maintains	Buy → Buy	—	$5.45	$5.60	+2.8%	+10.6%	+9.7%	+10.1%	+10.8%	+6.4%
May 11	HC Wainwright & Co.	Maintains	Buy → Buy	—	$6.17	$6.08	-1.4%	-0.2%	-6.6%	-4.9%	-3.4%	-11.7%
May 8	Morgan Stanley	Maintains	Overweight → Overweight	—	$6.35	$6.82	+7.4%	+1.6%	+3.0%	-2.8%	-3.1%	-9.3%
Mar 17	HC Wainwright & Co.	Maintains	Buy → Buy	—	$8.99	$8.91	-0.9%	-3.2%	+0.3%	-0.4%	-1.3%	+0.0%
Mar 16	Chardan Capital	Maintains	Buy → Buy	—	$9.16	$9.60	+4.8%	-1.9%	-5.0%	-1.5%	-2.2%	-3.2%
Dec 9	Morgan Stanley	Maintains	Equal Weight → Equal Weight	—	$15.23	$15.59	+2.4%	+1.9%	+0.5%	-4.1%	-2.1%	-6.4%
Dec 6	HC Wainwright & Co.	Maintains	Buy → Buy	—	$17.09	$17.14	+0.3%	-5.5%	-9.0%	-10.9%	-9.2%	-10.5%

Recent Filings

8-K · 7.01 ! Medium

Silence Therapeutics Plc American Depository Share -- 8-K 7.01: Regulation FD Disclosure

Silence Therapeutics updated its corporate presentation on March 5, 2026, with business updates now available on its investor relations website, providing shareholders with current company information.

Mar 5

Data updated apr 27, 2026 1:42am · Source: massive.com