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Portfolio (Quarterly) Guide ↗

Opaleye Management Inc.

· CIK 0001595855
13F Portfolio $707M AUM Filed Nov 14, 2025 EDGAR ↗ ← All Funds
Q4 2025 Q3 2025 · All 43 New
Page 3 of 3  ·  43 positions
# Ticker Company Sector Shares Value ↓ % Port Chg Shares Chg % Period Price ① Since Period ①
41 PEPG PEPGEN INC Healthcare 75,000.0 $346K 0.05% NEW $4.62 -69.9%
42 IBIO INC 375,000.0 $310K 0.04% NEW $0.83
43 ADGM ADAGIO MED HLDGS INC Healthcare 110,571.0 $215K 0.03% NEW $1.94 -57.0%
Page 3 of 3  ·  43 positions

Period Price is the implied market price on the last day of the reporting period, calculated as reported value ÷ shares held. It is not the fund's purchase price or cost basis — the fund may have initiated or added to the position at any point during the quarter at a different price. Since Period shows the price change from that quarter-end snapshot to today's last price — it reflects stock movement after the report date, not the fund's actual return.

Sector Allocation
Healthcare 100.0%